منابع مشابه
Opiates, sleep, and pain: the adenosinergic link.
BARRING a revolutionary breakthrough in pain management, opiates will remain the mainstay of analgesia for the foreseeable future. For years, researchers chasing the Holy Grail of opiate pharmacology have sought to dissociate their desirable analgesic properties from their undesirable ones. In addition to their well-known respiratory depressant effects and potential for addiction, opiates also ...
متن کاملEpidural opiates and degenerative back pain.
THE relief of acute pain by epidural and intrathecal opiates has been widely explored in the past few years. The existence of spinal opioid or endorphin receptor sites explains the excellent analgesia which can be achieved by these routes. It is interesting that endorphin levels in the cerebrospinal fluid have been shown to be markedly lower than normal in both acute and chronic pain.' Most stu...
متن کاملDissociable influences of opiates and expectations on pain.
Placebo treatments and opiate drugs are thought to have common effects on the opioid system and pain-related brain processes. This has created excitement about the potential for expectations to modulate drug effects themselves. If drug effects differ as a function of belief, this would challenge the assumptions underlying the standard clinical trial. We conducted two studies to directly examine...
متن کاملOptimizing use of opiates in the management of cancer pain
Cancer pain is often suboptimally managed. The underestimation and undertreatment continues to be a problem despite the availability of consensus-based guidelines. Most patients with cancer develop pain. The prevalence and severity of pain among cancer patients varies according to primary and metastatic sites and stage of disease. Opioid therapy is the cornerstone of management of severe chroni...
متن کاملSleep and pain.
Noxious stimuli and painful disorders interfere with sleep, but disturbances in sleep also contribute to the experience of pain.Chronic paroxysmal hemicrania and possibly cluster headaches are related to REM sleep. Whereas headache is associated with snoring and sleep apnea, morning headaches are not specific for any primary sleep disorder. Nevertheless, the management of the sleep disorder ame...
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ژورنال
عنوان ژورنال: Anesthesiology
سال: 2009
ISSN: 0003-3022
DOI: 10.1097/aln.0b013e3181bdfa2e